Publications

ORCID: 0000-0001-5227-2663; Scopus Author ID: 57200073811; Google Scholar: Yao Lin

64. S. Ekatan, T. Xue, Z. Song, T. Yang, D. Ndaya, M. Shaw, J. Cheng and Y. Lin, “Thermomechanical Properties of Solid ‘Liquid Crystalline’ Films from Hot-Pressed Synthetic Polypeptides of Various Macromolecular Architectures,” Macromolecules, in press (2024). https://doi.org/10.1021/acs.macromol.3c02005

Abstract TOC

63. T. Yang, T. Xue, J. Mao, Y. Chen, H. Tian, A. Bartolome, H. Xia, X. Yao, C. V. Kumar, J. Cheng and Y. Lin, “Tailoring Synthetic Polypeptide Design for Directed Fibril Superstructure Formation and Enhanced Hydrogel Properties,” Journal of the American Chemical Society, 146, 9, 5823-5833 (2024). https://doi.org/10.1021/jacs.3c10762

Abstract Image JACS Cover Image

62. W. Wang, H. Fu, Y. Lin, J. Cheng and Z. Song, “Cooperative Covalent Polymerization of N-carboxyanhydrides: from Kinetic Studies to Efficient Synthesis of Polypeptide Materials,” Accounts of Materials Research, 4, 604–615 (2023). https://doi.org/10.1021/accountsmr.3c00046

Cooperative Covalent Polymerization

61. H. Duan, Z. Jia, M. Liaqat, M. D. Mellor, H. Tan, M. Nieh, Y. Lin, S. Link, C. F. Landes and J. He, “Site-Specific Chemistry on Gold Nanorods: Curvature-Guided Surface Dewetting and Supracolloidal Polymerization,” ACS Nano, 7, 12788–12797 (2023). https://doi.org/10.1021/acsnano.3c03929

Abstract Image

60. J. Lu, Z. Xu, H. Fu, Y. Lin, H. Wang and H. Lu, “Room-Temperature Grafting from Synthesis of Protein-Polydisulfide Conjugates via Aggregation-Induced Polymerization,” Journal of the American Chemical Society, 144, 15709-15717 (2022). https://doi.org/10.1021/jacs.2c05997

AIP

59. H. Fu, R. Baumgartner, Z. Song, C. Chen, J. Cheng and Y. Lin, “Generalized Model of Cooperative Covalent Polymerization: Connecting the Supramolecular Binding Interactions with the Catalytic Behavior,” Macromolecules, 55, 2041-2050 (2022).  https://doi.org/10.1021/acs.macromol.1c02606

Abstract Image

58. T. Yang, K. Benson, H. Fu, T. Xue, Z. Song, H. Duan, H. Xia, A. Kalluri, J. He, J. Cheng, C. Kumar and Y. Lin, “Modeling and Designing Particle-regulated Amyloid-like Assembly of Synthetic Polypeptides in Aqueous Solution,” Biomacromolecules, 23, 196–209 (2022). https://doi.org/10.1021/acs.biomac.1c01230

Abstract Image

57. H. Duan, T. Malesky, J. Wang, C. Liu, H. Tan, M.P. Nieh, Y. Lin and J. He, “Patchy Metal Nanoparticles with Polymers: Controllable Growth and Two-Way Self-Assembly,” Nanoscale, 14, 7364-7371 (2022). https://doi.org/10.1039/D2NR01221A

Two-way assembly

56. H. Duan, C. Guan, J. Xue, T. Malesky, Y. Luo, Y. Lin, Y. Qin and J. He, “Facile synthesis of water-dispersible poly(3-hexylthiophene) nanoparticles with high yield and excellent colloidal stability,” iScience, 25, 104220 (2022). https://doi.org/10.1016/j.isci.2022.104220

P3HT Particle in water

55. H. Duan, Y. Lin and J. He, “Polymeric N-Heterocyclic Carbenes to Functionalize Plasmonic Metal Nanoparticles,” in World Scientific Reference on Plasmonic Nanomaterials Principles, Design and Bio-applications Vol. 3: Self-Assembly of Plasmonic Nanostructures, edited by Zhihong Nie, World Scientific Publishing (2022). https://doi.org/10.1142/12236-vol3 

54. H. Duan, Y. Lin and J. He, “Metal Nanoparticles Grafted with Polymeric Ligands: Self-assembly Guided by Polymers in Solution,” in Encyclopedia of Nanomaterials, Elsevier (2021). https://doi.org/10.1016/B978-0-12-822425-0.00004-X

Image 1

53. H. Duan, Q. Luo, Z. Wei, Y. Lin and J. He, “Symmetry-Broken Patches on Gold Nanoparticles through Deficient Ligand Exchange,” ACS Macro Letters10, 786-790 (2021). https://doi.org/10.1021/acsmacrolett.1c00252

Abstract Image

52. M. Anuganti, H. Fu, S. Ekatan, C. V. Kumar and Y. Lin, “Kinetic study on enzymatic hydrolysis of cellulose in an open, inhibition-free system,” Langmuir, 37, 5180–5192 (2021). https://doi.org/10.1021/acs.langmuir.1c00115

Abstract Image

51. Y. Xia, Z. Song, Z. Tan, T. Xue, S. Wei, L. Zhu, Y. Yang, H. Fu, Y. Jiang, Y. Lin, Y. Lu, A. L. Ferguson and J. Cheng,  “Accelerated polymerization of N-carboxyanhydrides catalyzed by crown ether,” Nature Communications, 12, 732 (2021). https://doi.org/10.1038/s41467-020-20724-w

Fig. 2

50. H. Xia, H. Fu, Y. Ren, R. Bordett, Y. Zhang, Y. Fu and Y. Lin, “Regulating the Supramolecular Polymerization of Fibrous Crystalline Structures in Aqueous Solution,” Macromolecular Rapid Communications, 42, 2000677 (2021). https://doi.org/10.1002/marc.202000677

crystalline fibrils

49. X. Lu, H. Fu, K. Shih, F. Jia Y. Sun, D. Wang, Y. Wang, S. Ekatan, M. Nieh, Y. Lin and K. Zhang, “DNA-mediated step-growth polymerization of bottlebrush macromonomers,” 142, 10297-10301 (2020). https://doi.org/10.1021/jacs.0c03806

Abstract Image

48. Z. Song, H. Fu, R. Baumgartner, L. Zhu, K. Shih, Y. Xia, X. Zheng, L. Yin, C. Chipot, Y. Lin and J. Cheng, “Enzyme-mimetic, self-catalyzed polymerization of polypeptide helices,” Nature Communications, 10, 5470 (2019). https://doi.org/10.1038/s41467-019-13502-w

47. Z. Song, H. Fu, J. Wang, J. Hui, T. Xue, L. A. Pacheco, H. Yane, R. Baumgartner, Z. Wang, Y. Xia, X. Wang, L. Yin, C. Chen, J. Rodríguez-López, A. L. Ferguson, Y. Lin, and J. Cheng, “Synthesis of polypeptides via bioinspired polymerization of in situ purified N-carboxyanhydrides,” Proceedings of the National Academy of Sciences of the United States of America, 116 (22) 10658-10663 (2019). https://doi.org/10.1073/pnas.1901442116

46. C. Chen, H. Fu, R. Baumgartner, Z. Song, Y. Lin and J. Cheng, “Proximity-induced Cooperative Polymerization of ‘Hinged’ Helical Polypeptides,” 141, 8680-8683 (2019). https://doi.org/10.1021/jacs.9b02298

45.  , R.  and 

Polymorphism in BTA supramolecular assemblies

44. Z. Song, H. Fu, R. Wang, L. A. Pacheco, X. Wang, Y. Lin and J. Cheng, “Secondary Structure in Synthetic Polypeptides from N-carboxyanhydrides: Design, Modulation, Assembly Behavior, and Materials Applications,” Chemical Society Reviews, 47, 7401-7425 (2018). https://doi.org/10.1039/C8CS00095F

Graphical abstract: Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications

43. M. K. Puglia, M. Anuganti, Y. Lin and C. V. Kumar, “A Simple Flow Reactor for Continuous Synthesis of Biographene for Enzymology Studies,” Methods in Enzymology, 609, 273-291 (2018). https://doi.org/10.1016/bs.mie.2018.08.015

42. P. Katyal, Y. Yang, Y. Fu, J. Iandosca, O. Vinogradova and Y. Lin, “Binding and Backbone Dynamics of Protein under Topological Constraint: Calmodulin as a Model System,” Chemical Communications, 54, 8917-8920 (2018). https://doi.org/10.1039/C8CC03977A

TM Parameters of l- and c-CaM

41. J. A. Modica, Y. Lin and M. Mrksich, “Synthesis of Cyclic Megamolecules,” Journal of the American Chemical Society, 140, 6391-6399 (2018). https://doi.org/10.1021/jacs.8b02665

synthesis of cyclic megamolecules

40. C. L. Baveghems, M. Anuganti, A. Pattammattel, Y. Lin and C. V. Kumar, “Tuning Enzyme/α-Zr(IV)Phosphate Nanoplate Interactions via Chemical Modification of Glucose Oxidase,” Langmuir, 34, 480-491 (2018). https://doi.org/10.1021/acs.langmuir.7b02919

charged based binding

39. H. Xia, H. Fu, Y. Zhang, K. Shih, Y. Ren, M. Anuganti, M. Nieh, J. Cheng, and Y. Lin, “Supramolecular Assembly of Comb-like Macromolecules Induced by Chemical Reactions that Modulate the Macromolecular Interactions in-situ,” Journal of the American Chemical Society, 139, 11106–11116  (2017). https://doi.org/10.1021/jacs.7b04986

Regulated Supramolecular Assembly

38. Z. Song, R. A. Mansbach, R. Baumgartner, K. Shih, H. He, N. Zhang, X. Ba, Y. Huang, D. Mani, Y. Lin, M. Nieh, A. L. Ferguson, L. Yin, and J. Cheng “Modulation of Polypeptide Conformation through Donor-Acceptor Transformation of Side-Chain Hydrogen Bonding Ligands,” Nature Communications, 8, 92, https://doi.org/10.1038/s41467-017-00079-5 (2017).

mechanistic scheme

37. Y. Ren, H. Fu, R. Baumgartner, Y. Zhang, J. Cheng, and Y. Lin, “Folding Cooperativity of Synthetic Polypeptides with or without “Tertiary” Interactions,” ACS Macro Letters, 6, 733–737 (2017). https://doi.org/10.1021/acsmacrolett.7b00324

cooperative interactions

36. Y. Ren, R. Baumgartner, H. Fu, P. Schoot, J. Cheng, and Y. Lin, “Revisiting the Folding Cooperativity of Synthetic Polypeptides in Solution,” Biomacromolecules, 18, 2324-2332 (2017). https://doi.org/10.1021/acs.biomac.7b00534

n-s diagram

35. R. Baumgartner, H. Fu, Z. Song, Y. Lin and J. Cheng, “Cooperative Polymerization of α-Helices Induced by Macromolecular Architecture,” Nature Chemistry,  9, 614-622 (2017). https://doi.org/10.1038/nchem.2712 [Cover Article] Volume 9 Issue 7

34. P. Katyal, Y. Yang, O. Vinogradova, and Y. Lin, “Expression of Cellulolytic Enzyme as a Fusion Protein that Reacts Specifically with Polymeric Scaffold,” Methods in Enzymology, 590, 259-276 (2017). https://doi.org/10.1016/bs.mie.2016.12.003

replacing protein scaffolds with macromolecules for functional enzyme complexes

33. F. Liu and Y. Lin, “Porous Polydivinylbenzene-based Solid Catalysts for Biomass Transformation Reactions,” in Nanoporous Catalysts for Biomass Conversion, edited by F. Xiao and L. Wang; Wiley (2017). https://doi.org/10.1002/9781119128113.ch6

Nanoporous Catalysts for Biomass Conversion (1119128080) cover image

32. M. Zeng, Y. Wang, Q. Liu, X. Yuan, S. Zuo, R. Feng, J. Yang, B. Wang, C. Qi, and Y. Lin, “Encaging Palladium Nanoparticles in Chitosan Modified Montmorillonite for Efficient, Recyclable Catalysts,” ACS Applied Materials & Interfaces, 8, 33157–33164 (2016). https://doi.org/10.1021/acsami.6b09895

Pd particles in chitosan

31. R. K. Kamat, Y. Zhang, M. Anuganti, W. Ma, I. Noshadi, H. Fu, S. Ekatan, R. Parnas, C. Wang, C. V. Kumar, and Y. Lin, “Enzymatic Activities of Polycatalytic Complexes with Nonprocessive Cellulases Immobilized on the Surface of Magnetic Nanoparticles,” Langmuir, 32, 11573-11579 (2016). https://doi.org/10.1021/acs.langmuir.6b02573

polycatalytic complexes

30. C. M. Riccardi, D. Mistri, O. Hart, M. Anuganti, Y. Lin, R. M. Kasi, and C. V. Kumar, “Covalent Interlocking of Glucose Oxidase and Peroxidase in the Voids of Paper: Enzyme–Polymer Spider Webs,” Chemical Communications, 52, 2593-2596 (2016). https://doi.org/10.1039/C6CC00037A

Graphical abstract: Covalent interlocking of glucose oxidase and peroxidase in the voids of paper: enzyme–polymer “spider webs”

29. L. Shao, Y. Ren, Z. Wang, C. Qi and Y. Lin, “Developing Chitosan-based Composite Nanofibers for Supporting Metal Catalysts,” Polymer, 75, 168-177 (2015). https://doi.org/10.1016/j.polymer.2015.08.031

Image for unlabelled figure

28. J. Zheng, Y. Li, Y. Sun, Y. Yang, Y. Ding, Y. Lin, and W. Yang, “A Generic Magnetic Microsphere Platform with ‘Clickable’ Ligands for Purification and Immobilization of Targeted Proteins,” ACS Applied Materials & Interfaces, 7, 7241–7250 (2015). https://doi.org/10.1021/acsami.5b00313

clickable ligands

27. R. Zhang, Z. Song, L. Yin, N. Zheng, H. Tang, H. Lu, N. P. Gabrielson, Y. Lin, K. Kim and J. Cheng, “Ionic-helical polypeptides toward nonviral gene delivery,” WIREs Nanomed Nanobiotechnol, 7, 98–110 (2015). https://doi.org/10.1002/wnan.1307

folding regulation

26. H. Lu, J. Wang, Z. Song, L. Yin, Y. Zhang, H. Tang, C. Tu, Y. Lin and J. Cheng, “Recent Advances in Amino Acid N-carboxyanhydrides and Synthetic Polypeptides: Chemistry, Self-assembly and Biological Applications,” Chemical Communications, 50, 139-155 (2014). https://doi.org/10.1039/C3CC46317F

25. J. Wang, H. Xia, Y. Zhang, H. Lu, R. Kamat, A. V. Dobrynin, J. Cheng & Y. Lin, “Nucleation-Controlled Polymerization of Nanoparticles into Supramolecular Structures,” Journal of the American Chemical Society, 135, 11417–11420 (2013). [Cover Article] https://doi.org/10.1021/ja402757e

24. R. K. Kamat, W. Ma, Y. Yang, Y. Zhang, C. Wang, C. V. Kumar & Y. Lin, “Adsorption and Hydrolytic Activity of Polycatalytic Cellulase Nano-complex on Cellulose,” ACS Applied Materials & Interfaces, 5, 8486–8494 (2013). https://doi.org/10.1021/am401916k

23. F. Liu, R. K. Kamat, I. Noshadi, D. Peck, R. Parnas, C. Qi & Y. Lin, “Depolymerization of Crystalline Cellulose Catalyzed by Acidic Ionic Liquids Grafted on Sponge-Like Nanoporous Polymers,” Chemical Communications, 49, 8456-8458 (2013). https://doi.org/10.1039/C3CC44703K

22. Y. Zhang, Q. Yin, H. Lu, H. Xia, Y. Lin & J. Cheng, “PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in Nanoparticle Surface PEGylation,” ACS Macro Letters, 2, 809-813 (2013). https://doi.org/10.1021/mz4003672

21. Y. Zhang, Y. Yang, W. Ma, J. Guo, Y. Lin & C. Wang, “Uniform Magnetic Core/Shell Microspheres Functionalized with Ni2+-Iminodiacetic Acid for One Step Purification and Immoblization of His-Tagged Enzymes,” ACS Applied Materials & Interfaces, 5, 2626-33 (2013). https://doi.org/10.1021/am4006786

20. J. Wang, H. Lu, Y. Ren, Y. Zhang, M. Morton, J. Cheng & Y. Lin, “Interrupted helical structures of grafted-polypeptides in brush-like macromolecules,” Macromolecules, 44, 8699–8708 (2011). https://doi.org/10.1021/ma201833b

19. J. Wang, H. Lu, R. Kamat, S. V. Pingali, V. S. Urban, J. Cheng & Y. Lin, “Supramolecular polymerization from polypeptide-grafted comb polymers,” Journal of the American Chemical Society, 133, 12906-12909 (2011). https://doi.org/10.1021/ja202268t

18. H. Lu, J. Wang, Y. Bai, J. W. Lang. S. Liu, Y. Lin & J. Cheng, “Ionic polypeptides with unusual helical stability,” Nature Communications, 2, 206, DOI: 10.1038/ncomms1209 (2011). https://doi.org/10.1038/ncomms1209

17. H. Lu, Y. Bai, J. Wang, N. P. Gabrielson, F. Wang, Y. Lin, and J. Cheng, “Ring-Opening Polymerization of γ-(4-Vinylbenzyl)-l-glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides,” Macromolecules, 44, 6237-6240 (2011). https://doi.org/10.1021/ma201164n

16. W. P. Hall, J. Modica, J. Anker, Y. Lin, M. Mrksich & R. P. Van Duyne, “A conformation- and ion-sensitive plasmonic biosensor,” Nano Letters, 11, 1098-1105 (2011). https://doi.org/10.1021/nl103994w

15. B. Luo, S. Xu, A. Luo, W. L. Wang, S. L. Wang, J. Guo, Y. Lin, D. Y. Zhao & C. C. Wang, “Mesoporous Biocompatible and acid-degradable magnetic colloidal nanocrystal clusters with sustainable stability and high hydrophobic drug loading capacity,” ACS Nano, 5, 1428-1435 (2011). https://doi.org/10.1021/nn103213y

14. Y. Zhang, H. Lu, Y. Lin & J. Cheng, “Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations,” Macromolecules, 44, 6641–6644 (2011). https://doi.org/10.1021/ma201678r

13. W. Ma, S. Xu, J. Li, J. Guo, Y. Lin & C. C. Wang, “Hydrophilic dual-responsive magnetite/PMAA core/shell microspheres with high magnetic susceptibility and pH sensitivity via distillation-precipitation polymerization,” Journal of Polymer Science Part A: Polymer Chemistry, 49, 2725-2733 (2011). https://doi.org/10.1002/pola.24705

12. H. Lu, J. Wang, Y. Lin & J. Cheng, “One-pot synthesis of brush-like polymers via integrated ring-opening metathesis polymerization and polymerization of amino acids N-carboxyanhydrides,” Journal of the American Chemical Society, 131, 13582-13593 (2009). https://doi.org/10.1021/ja903425x

2002-2008

11. W. P. Hall, J. N. Anker, Y. Lin, J. Modica, M. Mrksich & R. P. Van Duyne, “A calcium-modulated plasmonic switch,” Journal of the American Chemical Society, 130, 5836–5837 (2008). https://doi.org/10.1021/ja7109037

10. Y. Lin, A. Böker, J. He, K. Sill, H. Xiang, C. Abetz, X. Li, J. Wang, T. Emrick, S. Long, Q. Wang, A. Balazs & T.P. Russell, “Self-directed assembly of nanoparticles/copolymer mixtures,” Nature, 434, 55-59 (2005). https://doi.org/10.1038/nature03310

9. Y. Lin, A. Böker, H. Skaff, D. Cookson, A.D. Dinsmore, T. Emrick & T.P. Russell, “Structure and dynamics of nanoparticle assembly at liquid-liquid interfaces,” Langmuir, 21, 191-194 (2005). https://doi.org/10.1021/la048000q

Abstract Image

8. J.T. Russell, Y. Lin (co-first author), A. Böker, L. Su, P. Carl, H. Zettl, J. He, K. Sill, R. Tangirala, T. Emrick, K. Littrell, P. Thiyagarajan, D. Cookson, A. Fery, Q. Wang & T.P. Russell, “Self-assembly and cross-linking of bionanoparticles at liquid-liquid interfaces,” Angewandte Chemie International Edition, 44, 2420-2426 (2005). [Cover Article] https://doi.org/10.1002/anie.200462653

7. H. Skaff, Y. Lin, R. Tangirala, K. Breitenkamp, A. Böker, T.P. Russell & T. Emrick, “Crosslinked Capsules of Quantum Dots by Interfacial Assembly and Ligand Crosslinking,” Advanced Materials, 17, 2082-2086 (2005). https://doi.org/10.1002/adma.200500587

6. A. Böker, Y. Lin, K. Chiapperini, R. Horowitz, M. Thompson, V. Carreon, T. Xu, C. Abetz, H. Skaff, A.D. Dinsmore, T. Emrick & T.P. Russell, “Hierarchical nanoparticle assemblies formed by decorating breath figures,” Nature Materials, 3, 302-306 (2004). https://doi.org/10.1038/nmat1110

5. H. Xiang, Y. Lin & T. P. Russell, “Electrically induced patterning in block copolymer films,” Macromolecules, 37, 5358-5363 (2004). https://doi.org/10.1021/ma049888s

4. Y. Lin, H. Skaff, T. Emrick, A. D. Dinsmore & T. P. Russell, “Nanoparticle assembly and transport at liquid-liquid interfaces,” Science, 299, 226-229 (2003). https://doi.org/10.1126/science.1078616

3. Y. Lin, H. Skaff, A. Böker, T. Emrick, A. D. Dinsmore & T. P. Russell, “Ultrathin crosslinked nanoparticle membranes,” Journal of the American Chemical Society, 125, 12690-12691 (2003). https://doi.org/10.1021/ja036919a

2. L. Ding, F. E. Karasz, Y. Lin, Y. Pang & L. Liao “Photoluminescence and electroluminescence study of violet-blue and green emitting polymers and their blend,” Macromolecules, 36, 7301-7307 (2003). https://doi.org/10.1021/ma030237q

1. A. Meyer, N. Jones, Y. Lin & D. Kranbuehl, “Characterizing and modeling the hydrolysis of polyamide-11 in a pH 7 water environment,” Macromolecules, 35, 2784-2798 (2002). https://doi.org/10.1021/ma010541o