ORCID: 0000-0001-5227-2663; Scopus Author ID: 57200073811; Google Scholar: Yao Lin

62. W. Wang, H. Fu, Y. Lin, J. Cheng and Z. Song, “Cooperative Covalent Polymerization of N-carboxyanhydrides: from Kinetic Studies to Efficient Synthesis of Polypeptide Materials,” Accounts of Materials Research, in press (2023).

Cooperative Covalent Polymerization

61. H. Duan, Z. Jia, M. Liaqat, M. D. Mellor, H. Tan, M. Nieh, Y. Lin, S. Link, C. F. Landes and J. He, “Site-Specific Chemistry on Gold Nanorods: Curvature-Guided Surface Dewetting and Supracolloidal Polymerization,” ACS Nano, in press (2023).

60. J. Lu, Z. Xu, H. Fu, Y. Lin, H. Wang and H. Lu, “Room-Temperature Grafting from Synthesis of Protein-Polydisulfide Conjugates via Aggregation-Induced Polymerization,” Journal of the American Chemical Society, 144, 15709-15717 (2022).


59. H. Duan, T. Malesky, J. Wang, C. Liu, H. Tan, M.P. Nieh, Y. Lin and J. He, “Patchy Metal Nanoparticles with Polymers: Controllable Growth and Two-Way Self-Assembly,” Nanoscale, 14, 7364-7371 (2022).

Two-way assembly

58. H. Duan, C. Guan, J. Xue, T. Malesky, Y. Luo, Y. Lin, Y. Qin and J. He, “Facile synthesis of water-dispersible poly(3-hexylthiophene) nanoparticles with high yield and excellent colloidal stability,” iScience, 25, 104220 (2022).

P3HT Particle in water

57. H. Fu, R. Baumgartner, Z. Song, C. Chen, J. Cheng and Y. Lin, “Generalized Model of Cooperative Covalent Polymerization: Connecting the Supramolecular Binding Interactions with the Catalytic Behavior,” Macromolecules, 55, 2041-2050 (2022).

Abstract Image

56. T. Yang, K. Benson, H. Fu, T. Xue, Z. Song, H. Duan, H. Xia, A. Kalluri, J. He, J. Cheng, C. Kumar and Y. Lin, “Modeling and Designing Particle-regulated Amyloid-like Assembly of Synthetic Polypeptides in Aqueous Solution,” Biomacromolecules, 23, 196–209 (2022).

Abstract Image

55. H. Duan, Y. Lin and J. He, “Polymeric N-Heterocyclic Carbenes to Functionalize Plasmonic Metal Nanoparticles,” in World Scientific Reference on Plasmonic Nanomaterials Principles, Design and Bio-applications Vol. 3: Self-Assembly of Plasmonic Nanostructures, edited by Zhihong Nie, World Scientific Publishing (2022). 

54. H. Duan, Y. Lin and J. He, “Metal Nanoparticles Grafted with Polymeric Ligands: Self-assembly Guided by Polymers in Solution,” in Encyclopedia of Nanomaterials, Elsevier (2021).

Image 1

53. H. Duan, Q. Luo, Z. Wei, Y. Lin and J. He, “Symmetry-Broken Patches on Gold Nanoparticles through Deficient Ligand Exchange,” ACS Macro Letters10, 786-790 (2021).

Abstract Image

52. M. Anuganti, H. Fu, S. Ekatan, C. V. Kumar and Y. Lin, “Kinetic study on enzymatic hydrolysis of cellulose in an open, inhibition-free system,” Langmuir, 37, 5180–5192 (2021).

Abstract Image

51. Y. Xia, Z. Song, Z. Tan, T. Xue, S. Wei, L. Zhu, Y. Yang, H. Fu, Y. Jiang, Y. Lin, Y. Lu, A. L. Ferguson and J. Cheng,  “Accelerated polymerization of N-carboxyanhydrides catalyzed by crown ether,” Nature Communications, 12, 732 (2021).

Fig. 2

50. H. Xia, H. Fu, Y. Ren, R. Bordett, Y. Zhang, Y. Fu and Y. Lin, “Regulating the Supramolecular Polymerization of Fibrous Crystalline Structures in Aqueous Solution,” Macromolecular Rapid Communications, 42, 2000677 (2021).

crystalline fibrils

49. X. Lu, H. Fu, K. Shih, F. Jia Y. Sun, D. Wang, Y. Wang, S. Ekatan, M. Nieh, Y. Lin and K. Zhang, “DNA-mediated step-growth polymerization of bottlebrush macromonomers,” 142, 10297-10301 (2020).

Abstract Image

48. Z. Song, H. Fu, R. Baumgartner, L. Zhu, K. Shih, Y. Xia, X. Zheng, L. Yin, C. Chipot, Y. Lin and J. Cheng, “Enzyme-mimetic, self-catalyzed polymerization of polypeptide helices,” Nature Communications, 10, 5470 (2019).

47. Z. Song, H. Fu, J. Wang, J. Hui, T. Xue, L. A. Pacheco, H. Yane, R. Baumgartner, Z. Wang, Y. Xia, X. Wang, L. Yin, C. Chen, J. Rodríguez-López, A. L. Ferguson, Y. Lin, and J. Cheng, “Synthesis of polypeptides via bioinspired polymerization of in situ purified N-carboxyanhydrides,” Proceedings of the National Academy of Sciences of the United States of America, 116 (22) 10658-10663 (2019).

46. C. Chen, H. Fu, R. Baumgartner, Z. Song, Y. Lin and J. Cheng, “Proximity-induced Cooperative Polymerization of ‘Hinged’ Helical Polypeptides,” 141, 8680-8683 (2019).

45.  , R.  and 

Polymorphism in BTA supramolecular assemblies

44. Z. Song, H. Fu, R. Wang, L. A. Pacheco, X. Wang, Y. Lin and J. Cheng, “Secondary Structure in Synthetic Polypeptides from N-carboxyanhydrides: Design, Modulation, Assembly Behavior, and Materials Applications,” Chemical Society Reviews, 47, 7401-7425 (2018).

Graphical abstract: Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications

43. M. K. Puglia, M. Anuganti, Y. Lin and C. V. Kumar, “A Simple Flow Reactor for Continuous Synthesis of Biographene for Enzymology Studies,” Methods in Enzymology, 609, 273-291 (2018).

42. P. Katyal, Y. Yang, Y. Fu, J. Iandosca, O. Vinogradova and Y. Lin, “Binding and Backbone Dynamics of Protein under Topological Constraint: Calmodulin as a Model System,” Chemical Communications, 54, 8917-8920 (2018).

TM Parameters of l- and c-CaM

41. J. A. Modica, Y. Lin and M. Mrksich, “Synthesis of Cyclic Megamolecules,” Journal of the American Chemical Society, 140, 6391-6399 (2018).

synthesis of cyclic megamolecules

40. C. L. Baveghems, M. Anuganti, A. Pattammattel, Y. Lin and C. V. Kumar, “Tuning Enzyme/α-Zr(IV)Phosphate Nanoplate Interactions via Chemical Modification of Glucose Oxidase,” Langmuir, 34, 480-491 (2018).

charged based binding

39. H. Xia, H. Fu, Y. Zhang, K. Shih, Y. Ren, M. Anuganti, M. Nieh, J. Cheng, and Y. Lin, “Supramolecular Assembly of Comb-like Macromolecules Induced by Chemical Reactions that Modulate the Macromolecular Interactions in-situ,” Journal of the American Chemical Society, 139, 11106–11116  (2017).

Regulated Supramolecular Assembly

38. Z. Song, R. A. Mansbach, R. Baumgartner, K. Shih, H. He, N. Zhang, X. Ba, Y. Huang, D. Mani, Y. Lin, M. Nieh, A. L. Ferguson, L. Yin, and J. Cheng “Modulation of Polypeptide Conformation through Donor-Acceptor Transformation of Side-Chain Hydrogen Bonding Ligands,” Nature Communications, 8, 92, (2017).

mechanistic scheme

37. Y. Ren, H. Fu, R. Baumgartner, Y. Zhang, J. Cheng, and Y. Lin, “Folding Cooperativity of Synthetic Polypeptides with or without “Tertiary” Interactions,” ACS Macro Letters, 6, 733–737 (2017).

cooperative interactions

36. Y. Ren, R. Baumgartner, H. Fu, P. Schoot, J. Cheng, and Y. Lin, “Revisiting the Folding Cooperativity of Synthetic Polypeptides in Solution,” Biomacromolecules, 18, 2324-2332 (2017).

n-s diagram

35. R. Baumgartner, H. Fu, Z. Song, Y. Lin and J. Cheng, “Cooperative Polymerization of α-Helices Induced by Macromolecular Architecture,” Nature Chemistry,  9, 614-622 (2017). [Cover Article] Volume 9 Issue 7

34. P. Katyal, Y. Yang, O. Vinogradova, and Y. Lin, “Expression of Cellulolytic Enzyme as a Fusion Protein that Reacts Specifically with Polymeric Scaffold,” Methods in Enzymology, 590, 259-276 (2017).

replacing protein scaffolds with macromolecules for functional enzyme complexes

33. F. Liu and Y. Lin, “Porous Polydivinylbenzene-based Solid Catalysts for Biomass Transformation Reactions,” in Nanoporous Catalysts for Biomass Conversion, edited by F. Xiao and L. Wang; Wiley (2017).

Nanoporous Catalysts for Biomass Conversion (1119128080) cover image

32. M. Zeng, Y. Wang, Q. Liu, X. Yuan, S. Zuo, R. Feng, J. Yang, B. Wang, C. Qi, and Y. Lin, “Encaging Palladium Nanoparticles in Chitosan Modified Montmorillonite for Efficient, Recyclable Catalysts,” ACS Applied Materials & Interfaces, 8, 33157–33164 (2016).

Pd particles in chitosan

31. R. K. Kamat, Y. Zhang, M. Anuganti, W. Ma, I. Noshadi, H. Fu, S. Ekatan, R. Parnas, C. Wang, C. V. Kumar, and Y. Lin, “Enzymatic Activities of Polycatalytic Complexes with Nonprocessive Cellulases Immobilized on the Surface of Magnetic Nanoparticles,” Langmuir, 32, 11573-11579 (2016).

polycatalytic complexes

30. C. M. Riccardi, D. Mistri, O. Hart, M. Anuganti, Y. Lin, R. M. Kasi, and C. V. Kumar, “Covalent Interlocking of Glucose Oxidase and Peroxidase in the Voids of Paper: Enzyme–Polymer Spider Webs,” Chemical Communications, 52, 2593-2596 (2016).

Graphical abstract: Covalent interlocking of glucose oxidase and peroxidase in the voids of paper: enzyme–polymer “spider webs”

29. L. Shao, Y. Ren, Z. Wang, C. Qi and Y. Lin, “Developing Chitosan-based Composite Nanofibers for Supporting Metal Catalysts,” Polymer, 75, 168-177 (2015).

Image for unlabelled figure

28. J. Zheng, Y. Li, Y. Sun, Y. Yang, Y. Ding, Y. Lin, and W. Yang, “A Generic Magnetic Microsphere Platform with ‘Clickable’ Ligands for Purification and Immobilization of Targeted Proteins,” ACS Applied Materials & Interfaces, 7, 7241–7250 (2015).

clickable ligands

27. R. Zhang, Z. Song, L. Yin, N. Zheng, H. Tang, H. Lu, N. P. Gabrielson, Y. Lin, K. Kim and J. Cheng, “Ionic-helical polypeptides toward nonviral gene delivery,” WIREs Nanomed Nanobiotechnol, 7, 98–110 (2015).

folding regulation

26. H. Lu, J. Wang, Z. Song, L. Yin, Y. Zhang, H. Tang, C. Tu, Y. Lin and J. Cheng, “Recent Advances in Amino Acid N-carboxyanhydrides and Synthetic Polypeptides: Chemistry, Self-assembly and Biological Applications,” Chemical Communications, 50, 139-155 (2014).

25. J. Wang, H. Xia, Y. Zhang, H. Lu, R. Kamat, A. V. Dobrynin, J. Cheng & Y. Lin, “Nucleation-Controlled Polymerization of Nanoparticles into Supramolecular Structures,” Journal of the American Chemical Society, 135, 11417–11420 (2013). [Cover Article]

24. R. K. Kamat, W. Ma, Y. Yang, Y. Zhang, C. Wang, C. V. Kumar & Y. Lin, “Adsorption and Hydrolytic Activity of Polycatalytic Cellulase Nano-complex on Cellulose,” ACS Applied Materials & Interfaces, 5, 8486–8494 (2013).

23. F. Liu, R. K. Kamat, I. Noshadi, D. Peck, R. Parnas, C. Qi & Y. Lin, “Depolymerization of Crystalline Cellulose Catalyzed by Acidic Ionic Liquids Grafted on Sponge-Like Nanoporous Polymers,” Chemical Communications, 49, 8456-8458 (2013).

22. Y. Zhang, Q. Yin, H. Lu, H. Xia, Y. Lin & J. Cheng, “PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in Nanoparticle Surface PEGylation,” ACS Macro Letters, 2, 809-813 (2013).

21. Y. Zhang, Y. Yang, W. Ma, J. Guo, Y. Lin & C. Wang, “Uniform Magnetic Core/Shell Microspheres Functionalized with Ni2+-Iminodiacetic Acid for One Step Purification and Immoblization of His-Tagged Enzymes,” ACS Applied Materials & Interfaces, 5, 2626-33 (2013).

20. J. Wang, H. Lu, Y. Ren, Y. Zhang, M. Morton, J. Cheng & Y. Lin, “Interrupted helical structures of grafted-polypeptides in brush-like macromolecules,” Macromolecules, 44, 8699–8708 (2011).

19. J. Wang, H. Lu, R. Kamat, S. V. Pingali, V. S. Urban, J. Cheng & Y. Lin, “Supramolecular polymerization from polypeptide-grafted comb polymers,” Journal of the American Chemical Society, 133, 12906-12909 (2011).

18. H. Lu, J. Wang, Y. Bai, J. W. Lang. S. Liu, Y. Lin & J. Cheng, “Ionic polypeptides with unusual helical stability,” Nature Communications, 2, 206, DOI: 10.1038/ncomms1209 (2011).

17. H. Lu, Y. Bai, J. Wang, N. P. Gabrielson, F. Wang, Y. Lin, and J. Cheng, “Ring-Opening Polymerization of γ-(4-Vinylbenzyl)-l-glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides,” Macromolecules, 44, 6237-6240 (2011).

16. W. P. Hall, J. Modica, J. Anker, Y. Lin, M. Mrksich & R. P. Van Duyne, “A conformation- and ion-sensitive plasmonic biosensor,” Nano Letters, 11, 1098-1105 (2011).

15. B. Luo, S. Xu, A. Luo, W. L. Wang, S. L. Wang, J. Guo, Y. Lin, D. Y. Zhao & C. C. Wang, “Mesoporous Biocompatible and acid-degradable magnetic colloidal nanocrystal clusters with sustainable stability and high hydrophobic drug loading capacity,” ACS Nano, 5, 1428-1435 (2011).

14. Y. Zhang, H. Lu, Y. Lin & J. Cheng, “Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations,” Macromolecules, 44, 6641–6644 (2011).

13. W. Ma, S. Xu, J. Li, J. Guo, Y. Lin & C. C. Wang, “Hydrophilic dual-responsive magnetite/PMAA core/shell microspheres with high magnetic susceptibility and pH sensitivity via distillation-precipitation polymerization,” Journal of Polymer Science Part A: Polymer Chemistry, 49, 2725-2733 (2011).

12. H. Lu, J. Wang, Y. Lin & J. Cheng, “One-pot synthesis of brush-like polymers via integrated ring-opening metathesis polymerization and polymerization of amino acids N-carboxyanhydrides,” Journal of the American Chemical Society, 131, 13582-13593 (2009).


11. W. P. Hall, J. N. Anker, Y. Lin, J. Modica, M. Mrksich & R. P. Van Duyne, “A calcium-modulated plasmonic switch,” Journal of the American Chemical Society, 130, 5836–5837 (2008).

10. Y. Lin, A. Böker, J. He, K. Sill, H. Xiang, C. Abetz, X. Li, J. Wang, T. Emrick, S. Long, Q. Wang, A. Balazs & T.P. Russell, “Self-directed assembly of nanoparticles/copolymer mixtures,” Nature, 434, 55-59 (2005).

9. Y. Lin, A. Böker, H. Skaff, D. Cookson, A.D. Dinsmore, T. Emrick & T.P. Russell, “Structure and dynamics of nanoparticle assembly at liquid-liquid interfaces,” Langmuir, 21, 191-194 (2005).

Abstract Image

8. J.T. Russell, Y. Lin (co-first author), A. Böker, L. Su, P. Carl, H. Zettl, J. He, K. Sill, R. Tangirala, T. Emrick, K. Littrell, P. Thiyagarajan, D. Cookson, A. Fery, Q. Wang & T.P. Russell, “Self-assembly and cross-linking of bionanoparticles at liquid-liquid interfaces,” Angewandte Chemie International Edition, 44, 2420-2426 (2005). [Cover Article]

7. H. Skaff, Y. Lin, R. Tangirala, K. Breitenkamp, A. Böker, T.P. Russell & T. Emrick, “Crosslinked Capsules of Quantum Dots by Interfacial Assembly and Ligand Crosslinking,” Advanced Materials, 17, 2082-2086 (2005).

6. A. Böker, Y. Lin, K. Chiapperini, R. Horowitz, M. Thompson, V. Carreon, T. Xu, C. Abetz, H. Skaff, A.D. Dinsmore, T. Emrick & T.P. Russell, “Hierarchical nanoparticle assemblies formed by decorating breath figures,” Nature Materials, 3, 302-306 (2004).

5. H. Xiang, Y. Lin & T. P. Russell, “Electrically induced patterning in block copolymer films,” Macromolecules, 37, 5358-5363 (2004).

4. Y. Lin, H. Skaff, T. Emrick, A. D. Dinsmore & T. P. Russell, “Nanoparticle assembly and transport at liquid-liquid interfaces,” Science, 299, 226-229 (2003).

3. Y. Lin, H. Skaff, A. Böker, T. Emrick, A. D. Dinsmore & T. P. Russell, “Ultrathin crosslinked nanoparticle membranes,” Journal of the American Chemical Society, 125, 12690-12691 (2003).

2. L. Ding, F. E. Karasz, Y. Lin, Y. Pang & L. Liao “Photoluminescence and electroluminescence study of violet-blue and green emitting polymers and their blend,” Macromolecules, 36, 7301-7307 (2003).

1. A. Meyer, N. Jones, Y. Lin & D. Kranbuehl, “Characterizing and modeling the hydrolysis of polyamide-11 in a pH 7 water environment,” Macromolecules, 35, 2784-2798 (2002).